One ticket with five numbers, but missing the Mega number, was sold in Kentucky and is worth $1 million, according to the Multi-State Lottery Association, which conducts the game.
The numbers drawn Tuesday were 6, 9, 13, 29, 66 and the Mega number was 24. The estimated jackpot was $183 million.
The drawing was the 10th since the last time a ticket with all six numbers was sold.
The odds of matching all five numbers and the Mega number are 1 in 302,575,350, according to the California Lottery. The overall chance of winning a prize is 1 in 24.
The Mega Millions game is played in 45 states, the District of Columbia, and U.S. Virgin Islands.